We used the lesional steps in tumor progression and multi-variable logistic regression to
develop a prognostic model for primary, clinical stage I cutaneous melanoma. This model is 89…

Context Biochemical disease recurrence after radical prostatectomy often prompts salvage
radiotherapy, but no studies to date have had sufficient numbers of patients or follow-up to …

Objectives. —To identify predictors of utilization of breast-ovarian cancer susceptibility (BRCA1gene)
testing and to evaluate outcomes of participation in a testing program. Design. —…

BACKGROUND: Prior studies assessing the correlation of Gleason score (GS) at needle biopsy
and corresponding radical prostatectomy (RP) predated the use of the modified Gleason …

Purpose : Long-term prostate cancer specific mortality after radical prostatectomy is poorly
defined in the era of widespread screening. An understanding of the treated natural history of …

Results The median survival free of intervention was 6.5 years (range, 0.0 to 15.0 years)
after diagnosis, and the proportions of men remaining free of intervention after 2, 5, and 10 …

Background: High intake of soy foods has been proposed to contribute to the low breast
cancer risk in Asian countries. However, results of epidemiologic studies of this association are …

Background: P-glycoprotein (gp170; encoded by the MDR1 gene [also known as PGY1]) is
a membrane protein capable of exporting a variety of anticancer drugs from cells. MDR1/ …

OBJECTIVES: To update the 2001 “Partin tables” with a contemporary patient cohort and
revised variable categorization, correcting for the effects of stage migration. METHODS: We …

Whether colon cancer risk can be modified by a diet rich in vegetables, grains, and fruit, and,
if so, whether the protective factor is dietary fiber or other biologically active components …