Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to …

…, RH Shoemaker, BR O'Keefe… - Antimicrobial agents …, 1997 - Am Soc Microbiol
We have isolated and sequenced a novel 11-kDa virucidal protein, named cyanovirin-N (CV-N),
from cultures of the cyanobacterium (blue-green alga) Nostoc ellipsosporum. We also …

The logic of message design: Individual differences in reasoning about communication

BJ O'keefe - Communications Monographs, 1988 - Taylor & Francis
… (2.2b) This report is pretty good, but I think it needs some revision. I have listed some
suggestions for you, and I would appreciate it if you would look them over and try to respond to …

Polymerization of lactide and related cyclic esters by discrete metal complexes

BJ O'Keefe, MA Hillmyer, WB Tolman - Journal of the Chemical Society …, 2001 - pubs.rsc.org
This perspective highlights recent research on the preparation of polyesters by the ring-opening
polymerization of cyclic esters employing well-characterized metal complexes. …

[HTML][HTML] Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp.

T Mori, BR O'Keefe, RC Sowder, S Bringans… - Journal of Biological …, 2005 - ASBMB
Griffithsin (GRFT), a novel anti-HIV protein, was isolated from an aqueous extract of the red
alga Griffithsia sp. The 121-amino acid sequence of GRFT has been determined, and …

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

BR O'Keefe, B Giomarelli, DL Barnard… - Journal of …, 2010 - Am Soc Microbiol
Viruses of the family Coronaviridae have recently emerged through zoonotic transmission to
become serious human pathogens. The pathogenic agent responsible for severe acute …

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

BR O'Keefe, F Vojdani, V Buffa… - Proceedings of the …, 2009 - National Acad Sciences
To prevent sexually transmitted HIV, the most desirable active ingredients of microbicides are
antiretrovirals (ARVs) that directly target viral entry and avert infection at mucosal surfaces. …

Mechanistic comparison of cyclic ester polymerizations by novel iron (III)− alkoxide complexes: single vs multiple site catalysis

BJ O'Keefe, LE Breyfogle, MA Hillmyer… - Journal of the …, 2002 - ACS Publications
The complexes Fe 2 (OCHPh 2 ) 6 and L 2 FeOR (R = Et or CHPh 2 , L = N,N‘-bis(trimethylsilyl)benzamidinate)
were structurally characterized, and comparative studies of the behavior …

[PDF][PDF] Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology: glycan-dependent gp120/protein interactions

…, DM Ratner, HR Bokesch, JB McMahon, BR O'Keefe… - Chemistry & biology, 2004 - cell.com
Defining HIV envelope glycoprotein interactions with host factors or binding partners
advances our understanding of the infectious process and provides a basis for the design of …

The relationship of work avoidance and learning goals to perceived competence, externality and meaning

TL Seifert, BA O'Keefe - British Journal of Educational …, 2001 - Wiley Online Library
Background. Motivational researchers have suggested that work avoidance may be an
academic goal in which students seek to minimise the amount of work they do in school. …

A Potent Novel Anti-HIV Protein from the Cultured Cyanobacterium Scytonema varium

HR Bokesch, BR O'Keefe, TC McKee, LK Pannell… - Biochemistry, 2003 - ACS Publications
A new anti-HIV protein, scytovirin, was isolated from aqueous extracts of the cultured
cyanobacterium Scytonema varium. The protein displayed potent anticytopathic activity against …