Study Objectives: We sought to provide an updated systematic review and meta-analysis of
studies investigating the effect of positive airway pressure (PAP) treatment for obstructive …

Acetazolamide improves loop gain but not the other physiological traits causing obstructive
sleep apnoea - Edwards - 2012 - The Journal of Physiology - Wiley Online Library …

Aging effects on sleep are important to consider for the practicing pulmonologist due to the
increase in prevalence of major respiratory disorders as well as the normal changes that …

There is not a clinically available technique for measuring the physiological traits causing
obstructive sleep apnea (OSA). Therefore, it is often difficult to determine why an individual has …

Rationale: A low respiratory arousal threshold (ArTH) is one of several traits involved in
obstructive sleep apnea pathogenesis and may be a therapeutic target; however, there is no …

Elevated loop gain, consequent to hypersensitive ventilatory control, is a primary nonanatomical
cause of obstructive sleep apnoea (OSA) but it is not possible to quantify this in the clinic…

We previously published a method for measuring several physiological traits causing obstructive
sleep apnea (OSA). The method, however, had a relatively low success rate (76%) and …

Rationale: There is currently no effective pharmacological treatment for obstructive sleep
apnea (OSA). Recent investigations indicate that drugs with noradrenergic and antimuscarinic …

Rationale: Oral appliances (OAs) are commonly used as an alternative treatment to continuous
positive airway pressure for patients with obstructive sleep apnea (OSA). However, OAs …

Rationale: Therapies for obstructive sleep apnea (OSA) could be administered on the basis
of a patient’s own phenotypic causes (“traits”) if a clinically applicable approach were …