Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty.
…, DJ Kereiakes, NS Kleiman, JD Talley, AL Wang… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Thrombosis has been implicated as central to the clinical complications of
coronary angioplasty (PTCA). Chimeric monoclonal 7E3 Fab (c7E3 Fab) is the first of a new …
coronary angioplasty (PTCA). Chimeric monoclonal 7E3 Fab (c7E3 Fab) is the first of a new …
Long-term protection from myocardial ischemic events in a randomized trial of brief integrin β3 blockade with percutaneous coronary intervention
…, SG Ellis, NS Kleiman, RJ Ivanhoe, AL Wang… - Jama, 1997 - jamanetwork.com
Context. —Avciximab,lonal antibody fragment against the platelet receptor α llb β 3 integrin,
prevents platelet aggregation. A randomized, placebo-controlled study showed that …
prevents platelet aggregation. A randomized, placebo-controlled study showed that …
[HTML][HTML] Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus …
NS Kleiman, AE Raizner, R Jordan, AL Wang… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: This study sought to describe in detail the pharmacokinetics and pharmacodynamics
of chimeric monoclonal 7E3 Fab (c7E3 Fab) and to compare platelet responses to …
of chimeric monoclonal 7E3 Fab (c7E3 Fab) and to compare platelet responses to …
Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond
INTRODUCTION Total synthesis of designer chromosomes and genomes is a new paradigm
for the study of genetics and biological systems. The Sc2.0 project is building a designer …
for the study of genetics and biological systems. The Sc2.0 project is building a designer …
IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype
Improvements in the quality and fitness of chimeric antigen receptor (CAR)-engineered T
cells, through CAR design or manufacturing optimizations, could enhance the therapeutic …
cells, through CAR design or manufacturing optimizations, could enhance the therapeutic …
Engineering the ribosomal DNA in a megabase synthetic chromosome
…, G Zhao, Z Luo, Y Lin, L Wang, Y Guo, A Wang… - Science, 2017 - science.org
INTRODUCTION It has long been an interesting question whether a living cell can be
constructed from scratch in the lab, a goal that may not be realized anytime soon. Nonetheless, …
constructed from scratch in the lab, a goal that may not be realized anytime soon. Nonetheless, …
Using a genetic algorithm to solve the generalized orienteering problem
… In this section, we compare our GA with a sophisticated artificial neural network model (ANN)
[7]. The ANN is a modified, continuous Hopfield neural network which uses discrete-time …
[7]. The ANN is a modified, continuous Hopfield neural network which uses discrete-time …
Near-infrared spectroscopy and imaging in food quality and safety
… The experimental results indicated that good classification rates were achieved using
PLS-DA and ANN, and best results were obtained using SVM. Wang and Paliwal examined the …
PLS-DA and ANN, and best results were obtained using SVM. Wang and Paliwal examined the …
Reliable multi-objective optimization of high-speed WEDM process based on Gaussian process regression
J Yuan, K Wang, T Yu, M Fang - International Journal of Machine Tools and …, 2008 - Elsevier
… , it is costly to sample enough data to support the accuracy of ANN models. Even so, a
proportional samples should be reserved as validation set for tuning ANN model parameters. …
proportional samples should be reserved as validation set for tuning ANN model parameters. …
Characterization of clonogenic multiple myeloma cells
The identity of the cells responsible for the initiation and maintenance of multiple myeloma (MM)
remains unclear largely because of the difficulty growing MM cells in vitro and in vivo. …
remains unclear largely because of the difficulty growing MM cells in vitro and in vivo. …