User profiles for Angela Yang
Angela Wei Hong YangRMIT University Verified email at rmit.edu.au Cited by 1184 |
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
…, T Foroud, JN McClintick, BM McGee, AY Yang… - Nature, 2001 - nature.com
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening systemic illness of abrupt
onset and unknown cause. Proteolysis of the blood-clotting protein von Willebrand factor (VWF…
onset and unknown cause. Proteolysis of the blood-clotting protein von Willebrand factor (VWF…
Plasminogen is a critical host pathogenicity factor for group A streptococcal infection
…, JW Homeister, WP Fay, NC Engleberg, AY Yang… - Science, 2004 - science.org
Group A streptococci, a common human pathogen, secrete streptokinase, which activates
the host's blood clot–dissolving protein, plasminogen. Streptokinase is highly specific for …
the host's blood clot–dissolving protein, plasminogen. Streptokinase is highly specific for …
Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40
H Yang, X Jiang, B Li, HJ Yang, M Miller, A Yang… - Nature, 2017 - nature.com
The mechanistic target of rapamycin complex 1 (mTORC1) controls cell growth and metabolism
in response to nutrients, energy levels, and growth factors. It contains the atypical kinase …
in response to nutrients, energy levels, and growth factors. It contains the atypical kinase …
[HTML][HTML] ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
…, D Zarabanda, SS Dholakia, A Yang… - Nature …, 2020 - nature.com
The coronavirus SARS-CoV-2 is the causative agent of the ongoing severe acute respiratory
disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the …
disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the …
Anti-tumor activity of splice-switching oligonucleotides
Alternative splicing has emerged as an important target for molecular therapies. Splice-switching
oligonucleotides (SSOs) modulate alternative splicing by hybridizing to pre-mRNA …
oligonucleotides (SSOs) modulate alternative splicing by hybridizing to pre-mRNA …
Yolk–shell nanostructure: an ideal architecture to achieve harmonious integration of magnetic–plasmonic hybrid theranostic platform
Magnetic–plasmonic hybrid nanoparticles (MPHNs) have attracted great interest in cancer
theranostics. However, the relaxivity of the magnetic component is typically reduced by the …
theranostics. However, the relaxivity of the magnetic component is typically reduced by the …
[HTML][HTML] Phellodendri cortex: a phytochemical, pharmacological, and pharmacokinetic review
Background. Phellodendri Cortex (PC) or Huang Bai. According to the scientific database of
China Plant Species and Chinese pharmacopeia 2015 edition, PC has two main species …
China Plant Species and Chinese pharmacopeia 2015 edition, PC has two main species …
[PDF][PDF] Nucleus accumbens cell type-and input-specific suppression of unproductive reward seeking
CK Lafferty, AK Yang, JA Mendoza, JP Britt - Cell Reports, 2020 - cell.com
The nucleus accumbens (NAc) contributes to behavioral inhibition and compulsions, but
circuit mechanisms are unclear. Recent evidence suggests that amygdala and thalamic inputs …
circuit mechanisms are unclear. Recent evidence suggests that amygdala and thalamic inputs …
The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival
KM Dougherty, JM Pearson, AY Yang… - Proceedings of the …, 1999 - National Acad Sciences
Plasminogen activator inhibitor-2 (PAI-2), a member of the serpin gene family, is thought to
serve as a primary regulator of plasminogen activation in the extravascular compartment. …
serve as a primary regulator of plasminogen activation in the extravascular compartment. …
Spontaneous thrombosis in mice carrying the factor V Leiden mutation
…, AY Yang, AA Purkayastha, TL Yang… - Blood, The Journal …, 2000 - ashpublications.org
A polymorphism in coagulation factor V, factor V Leiden (FVL), is the major known genetic
risk factor for thrombosis in humans. Approximately 10% of mutation carriers experience …
risk factor for thrombosis in humans. Approximately 10% of mutation carriers experience …