User profiles for Abel Kho
Abel KhoProfessor, Northwestern University Verified email at nm.org Cited by 10471 |
Defining the role of common variation in the genomic and biological architecture of adult human height
…, J Jolley, T Juliusdottir, J Junttila, AN Kho… - Nature …, 2014 - nature.com
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide
significance that together explained one-fifth of the heritability for adult height. By testing …
significance that together explained one-fifth of the heritability for adult height. By testing …
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
…, MA Basford, DS Carrell, PL Peissig, AN Kho… - Nature …, 2013 - nature.com
Candidate gene and genome-wide association studies (GWAS) have identified genetic variants
that modulate risk for human disease; many of these associations require further study to …
that modulate risk for human disease; many of these associations require further study to …
Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network
KM Newton, PL Peissig, AN Kho… - Journal of the …, 2013 - academic.oup.com
Background Genetic studies require precise phenotype definitions, but electronic medical
record (EMR) phenotype data are recorded inconsistently and in a variety of formats. Objective …
record (EMR) phenotype data are recorded inconsistently and in a variety of formats. Objective …
Design and implementation of a privacy preserving electronic health record linkage tool in Chicago
Objective To design and implement a tool that creates a secure, privacy preserving linkage of
electronic health record (EHR) data across multiple sites in a large metropolitan area in the …
electronic health record (EHR) data across multiple sites in a large metropolitan area in the …
Primary care practices' abilities and challenges in using electronic health record data for quality improvement
…, ST Edwards, WY Wu, H Pham-Singer, AN Kho… - Health …, 2018 - healthaffairs.org
Federal value-based payment programs require primary care practices to conduct quality
improvement activities, informed by the electronic reports on clinical quality measures that their …
improvement activities, informed by the electronic reports on clinical quality measures that their …
CAPriCORN: Chicago area patient-centered outcomes research network
The Chicago Area Patient-Centered Outcomes Research Network (CAPriCORN) represents
an unprecedented collaboration across diverse healthcare institutions including private, …
an unprecedented collaboration across diverse healthcare institutions including private, …
Electronic medical records for genetic research: results of the eMERGE consortium
AN Kho, JA Pacheco, PL Peissig… - Science translational …, 2011 - science.org
Clinical data in electronic medical records (EMRs) are a potential source of longitudinal
clinical data for research. The Electronic Medical Records and Genomics Network (eMERGE) …
clinical data for research. The Electronic Medical Records and Genomics Network (eMERGE) …
Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study
AN Kho, MG Hayes, L Rasmussen-Torvik… - Journal of the …, 2012 - academic.oup.com
Objective: Genome-wide association studies (GWAS) require high specificity and large numbers
of subjects to identify genotype–phenotype correlations accurately. The aim of this study …
of subjects to identify genotype–phenotype correlations accurately. The aim of this study …
[PDF][PDF] Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome-and phenome-wide studies
We repurposed existing genotypes in DNA biobanks across the Electronic Medical Records
and Genomics network to perform a genome-wide association study for primary …
and Genomics network to perform a genome-wide association study for primary …
Electronic health records-driven phenotyping: challenges, recent advances, and perspectives
With the completion of the Human Genome Project1 as well as recent advances in genomic
science and comparative biological studies, a new era of individualized medicine is evolving …
science and comparative biological studies, a new era of individualized medicine is evolving …