User profiles for A. Radhakrishnan

Arun Radhakrishnan

- Verified email at utsouthwestern.edu - Cited by 7331

Aparna Radhakrishnan

- Verified email at uw.edu - Cited by 2000

[HTML][HTML] Condensed complexes of cholesterol and phospholipids

HM McConnell, A Radhakrishnan - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
There is overwhelming evidence that lipid bilayer regions of animal cell membranes are in a
liquid state. Quantitative models of these bilayer regions must then be models of liquids. …

Retrospective on cholesterol homeostasis: the central role of scap

MS Brown, A Radhakrishnan… - Annual review of …, 2018 - annualreviews.org
Scap is a polytopic membrane protein that functions as a molecular machine to control the
cholesterol content of membranes in mammalian cells. In the 21 years since our laboratory …

[HTML][HTML] Current concepts of neurodegenerative mechanisms in Alzheimer's disease

KB Magalingam, A Radhakrishnan, NS Ping… - BioMed research …, 2018 - hindawi.com
Neurodegenerative diseases are hereditary or sporadic conditions that result in the
progressive loss of the structure and function of neurons as well as neuronal death. Although a …

The GFDL Earth System Model version 4.1 (GFDL‐ESM 4.1): Overall coupled model description and simulation characteristics

…, J Ploshay, A Radhakrishnan… - Journal of Advances …, 2020 - Wiley Online Library
We describe the baseline coupled model configuration and simulation characteristics of
GFDL's Earth System Model Version 4.1 (ESM4.1), which builds on component and coupled …

New gene functions in megakaryopoiesis and platelet formation

C Gieger, A Radhakrishnan, A Cvejic, W Tang, E Porcu… - Nature, 2011 - nature.com
Platelets are the second most abundant cell type in blood and are essential for maintaining
haemostasis. Their count and volume are tightly controlled within narrow physiological …

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

A Radhakrishnan, Y Ikeda, HJ Kwon… - Proceedings of the …, 2007 - National Acad Sciences
Cholesterol synthesis in animals is controlled by the regulated transport of sterol regulatory
element-binding proteins (SREBPs) from the endoplasmic reticulum to the Golgi, where the …

Seventy-five genetic loci influencing the human red blood cell

…, DS Paul, U Elling, H Allayee, X Li, A Radhakrishnan… - Nature, 2012 - nature.com
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment,
growth retardation and impaired physical capacity. To understand further the genetic factors …

A draft map of the human proteome

…, LDN Selvan, AH Patil, V Nanjappa, A Radhakrishnan… - Nature, 2014 - nature.com
The availability of human genome sequence has transformed biomedical research over the
past decade. However, an equivalent map for the human proteome with direct …

[HTML][HTML] Structure and interactions of the human programmed cell death 1 receptor

X Cheng, V Veverka, A Radhakrishnan… - Journal of Biological …, 2013 - ASBMB
PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune
responses and a promising therapeutic target. The structure and interactions of human PD…

A large focus of naturally acquired Plasmodium knowlesi infections in human beings

B Singh, LK Sung, A Matusop, A Radhakrishnan… - The Lancet, 2004 - thelancet.com
Background About a fifth of malaria cases in 1999 for the Kapit division of Malaysian Borneo
had routinely been identified by microscopy as Plasmodium malariae, although these …