Stress and depressive symptoms prospectively predict immune change among HIV-seropositive men. HIV Neurobehavioral Research Center Group

Psychiatry. 1995 Nov;58(4):299-312. doi: 10.1080/00332747.1995.11024735.

Abstract

LIFE stress, mood, and other psychosocial factors may help to explain variability in HIV (human immunodeficiency virus) disease progression. Attempts to support this notion empirically have produced mixed findings; several studies report a positive relationship between psychosocial factors and various indicators of disease progression or immune function (e.g., Evans et al. 1992; Goodkin et. al. 1992), whereas others have failed to detect any association (e.g., Perry et. al. 1992).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Arousal / physiology
  • CD4 Lymphocyte Count*
  • CD8-Positive T-Lymphocytes / immunology*
  • Defense Mechanisms
  • Depression / immunology
  • Depression / psychology*
  • HIV Antibodies / blood
  • HIV Infections / immunology
  • HIV Infections / psychology*
  • HIV-1 / immunology*
  • Humans
  • Life Change Events*
  • Lymphocyte Count
  • Male
  • Middle Aged
  • Personality Assessment
  • beta 2-Microglobulin / analysis*

Substances

  • HIV Antibodies
  • beta 2-Microglobulin