Abstract
On expression cloning in Xenopus oocytes, the renal cDNA expressed functionally in both the rat and human proximal tubule yields an amino acid transporter with properties generally consistent with representation of the cystinuria gene.
MeSH terms
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Amino Acid Transport Systems, Basic*
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Amino Acids / metabolism*
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Animals
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Biological Transport
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Carrier Proteins / metabolism*
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Cloning, Molecular
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Cystinuria / genetics*
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DNA, Complementary / genetics
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Gene Expression Regulation*
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Humans
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Membrane Glycoproteins / metabolism*
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Oocytes / metabolism
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Rats
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Xenopus
Substances
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Amino Acid Transport Systems, Basic
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Amino Acids
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Carrier Proteins
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DNA, Complementary
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Membrane Glycoproteins
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SLC7A9 protein, human