Reliability of the Center for Epidemiologic Studies Depression Scale, a 20-item symptom checklist, is examined using data from a sample of community respondents containing Anglos (254), Blacks (270), and Mexican Americans (181). Although the survey response rate was lower for Mexican Americans, quality of the data provided by this group was not significantly different from that for Anglos or Blacks. That is, there were no differences among these groups in terms of missing data or internal consistency reliabilty (as measured by Cronbach's alpha and Spearman-Brown split halves). Factor-analytic results also demonstrate the same general structure of responses among the three groups.