Depression and treatment among U.S. pregnant and nonpregnant women of reproductive age, 2005-2009

J Womens Health (Larchmt). 2012 Aug;21(8):830-6. doi: 10.1089/jwh.2011.3466. Epub 2012 Jun 12.

Abstract

Background: Depression is often undiagnosed and untreated. It is not clear if differences exist in the diagnosis and treatment of depression among pregnant and nonpregnant women. We sought to estimate the prevalence of undiagnosed depression, treatment by modality, and treatment barriers by pregnancy status among U.S. reproductive-aged women.

Methods: We identified 375 pregnant and 8,657 nonpregnant women 18-44 years of age who met criteria for past-year major depressive episode (MDE) from 2005-2009 nationally representative data. Chi-square statistics and adjusted prevalence ratios (aPR) were calculated.

Results: MDE in pregnant women (65.9%) went undiagnosed more often than in nonpregnant women (58.6%) (aPR 1.1, 95% confidence interval [CI] 1.0-1.3). Half of depressed pregnant (49.6%) and nonpregnant (53.7%) women received treatment (aPR 1.0, 95% CI 0.90-1.1), with prescription medication the most common form for both pregnant (39.6%) and nonpregnant (47.4%) women. Treatment barriers did not differ by pregnancy status and were cost (54.8%), opposition to treatment (41.7%), and stigma (26.3%).

Conclusions: Pregnant women with MDE were no more likely than nonpregnant women to be diagnosed with or treated for their depression.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Activities of Daily Living
  • Adolescent
  • Adult
  • Chi-Square Distribution
  • Counseling / statistics & numerical data
  • Cross-Sectional Studies
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / drug therapy
  • Depressive Disorder, Major / epidemiology*
  • Depressive Disorder, Major / therapy*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Health Surveys
  • Healthcare Disparities / statistics & numerical data*
  • Healthcare Disparities / trends
  • Humans
  • Insurance Coverage / statistics & numerical data
  • Maternal Age*
  • Mental Health Services / economics
  • Mental Health Services / statistics & numerical data
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / therapy*
  • Pregnant Women / psychology*
  • Prescription Drugs / therapeutic use
  • Prevalence
  • Reproductive Health*
  • Residence Characteristics
  • Socioeconomic Factors
  • Surveys and Questionnaires
  • United States / epidemiology

Substances

  • Prescription Drugs