Nausea and vomiting of pregnancy

Noel M Lee; Sumona Saha

doi:10.1016/j.gtc.2011.03.009

Nausea and vomiting of pregnancy

Gastroenterol Clin North Am. 2011 Jun;40(2):309-34, vii. doi: 10.1016/j.gtc.2011.03.009.

Authors

Noel M Lee¹, Sumona Saha

Affiliation

¹ University of Wisconsin School of Medicine and Public Health, Division of Gastroenterology and Hepatology, UW Medical Foundation Centennial Building, 1685 Highland Avenue, Room 4224, Madison, WI 53705, USA.

Abstract

Nausea and vomiting are common experiences in pregnancy, affecting 70% to 80% of all pregnant women. Various metabolic and neuromuscular factors have been implicated in the pathogenesis of nausea and vomiting of pregnancy (NVP) and hyperemesis gravidarum (HG), an entity distinct from NVP. However, their exact cause is unknown. Consequently, treatment of NVP and HG can be difficult, as neither the optimal targets for treatment nor the full effects of potential treatments on the developing fetus are known. This article reviews the epidemiology, pathology, diagnosis, outcomes, and treatment of NVP and HG.

Publication types

Review

MeSH terms

Female
Humans
Nausea / etiology*
Nausea / therapy
Pregnancy
Pregnancy Complications*
Risk Factors
Vomiting / etiology*
Vomiting / therapy

Grants and funding

K12 HD055894/HD/NICHD NIH HHS/United States