Abstract
Background:
Transient sub-aponeurotic fluid collections are rarely recognized lesions that may be frequently related to traumatic labor and occur within weeks after birth. Their etiology has remained uncertain.
Methods and results:
Here we report on five new cases with typical clinical findings and normal neuroimaging. A detailed analysis of the lesion aspirates was performed in three patients, always revealing beta(2)-transferrin and high concentrations of beta-trace protein.
Conclusions:
This indicates that cerebrospinal fluid leakage contributes to this rare condition. All lesions disappeared spontaneously within 2-5 months so that conservative treatment seems appropriate.
MeSH terms
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Age of Onset
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Birth Injuries / diagnostic imaging
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Birth Injuries / pathology*
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Cerebrospinal Fluid / physiology*
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Female
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Fistula / diagnostic imaging
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Fistula / etiology
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Fistula / pathology*
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Humans
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Infant
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Intramolecular Oxidoreductases / analysis
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Intramolecular Oxidoreductases / metabolism
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Lipocalins / analysis
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Lipocalins / metabolism
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Magnetic Resonance Imaging
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Male
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Scalp / anatomy & histology
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Scalp / diagnostic imaging
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Scalp / pathology*
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Subarachnoid Space / pathology
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Subarachnoid Space / physiopathology
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Time Factors
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Tomography, X-Ray Computed
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Transferrin / analysis
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Transferrin / metabolism
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Ultrasonography
Substances
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Lipocalins
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Transferrin
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Intramolecular Oxidoreductases
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prostaglandin R2 D-isomerase