The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study

MeSH terms

• Aldosterone / blood
• Double-Blind Method
• Eplerenone
• Heart Failure / drug therapy*
• Heart Failure / etiology
• Heart Failure / pathology
• Humans
• Mineralocorticoid Receptor Antagonists / administration & dosage
• Mineralocorticoid Receptor Antagonists / adverse effects
• Mineralocorticoid Receptor Antagonists / therapeutic use*
• Multicenter Studies as Topic
• Myocardial Infarction / complications*
• Randomized Controlled Trials as Topic
• Research Design
• Sample Size
• Spironolactone / administration & dosage
• Spironolactone / adverse effects
• Spironolactone / analogs & derivatives*
• Spironolactone / therapeutic use*
• Survival Analysis
• Systole