Predictors of conversion to sinus rhythm using ibutilide for atrial fibrillation or flutter

Am J Cardiol. 2000 Jan 1;85(1):112-4, A9. doi: 10.1016/s0002-9149(99)00619-0.

Abstract

To determine what factors can predict conversion to sinus rhythm, we retrospectively studied 201 consecutive patients who received ibutilide for treatment of atrial fibrillation or flutter. On multivariate analysis, the following factors were significantly associated with conversion: recent onset of arrhythmia, an underlying atrial flutter rhythm, lack of a history of congestive heart failure, and lack of concomitant digoxin therapy.

MeSH terms

  • Aged
  • Anti-Arrhythmia Agents / pharmacology
  • Anti-Arrhythmia Agents / therapeutic use*
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / drug therapy*
  • Atrial Fibrillation / physiopathology
  • Atrial Flutter / diagnosis*
  • Atrial Flutter / drug therapy*
  • Atrial Flutter / physiopathology
  • Chi-Square Distribution
  • Electrocardiography / methods
  • Female
  • Heart Rate
  • Humans
  • Logistic Models
  • Male
  • Multivariate Analysis
  • Predictive Value of Tests
  • Retrospective Studies
  • Risk Factors
  • Sulfonamides / pharmacology
  • Sulfonamides / therapeutic use*
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Arrhythmia Agents
  • Sulfonamides
  • ibutilide