Heart failureClinical and Prognostic Value of Duke's Activity Status Index Along With Plasma B-Type Natriuretic Peptide Levels in Chronic Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy
Section snippets
Methods
One hundred thirty consecutive patients with HF (of ischemic or idiopathic dilated cardiomyopathy origin) hospitalized for clinical worsening of HF symptoms (mean age 64 ± 12 years), with a mean echocardiographically documented left ventricular ejection fraction of 26 ± 7%, were studied. The study protocol was approved by the institutional ethics committee, and all patients enrolled gave informed written consent.
These patients underwent complete history interviews and physical examinations.
Results
The baseline characteristics of the study population are listed in Table 2. Seventy-seven of 130 patients experienced major cardiovascular events after a median time of 60 days. Patients experiencing events were in higher NYHA classes (p = 0.001) and had shorter 6-minute walking distances (p = 0.041), lower ejection fractions (p <0.001), higher plasma BNP at hospital admission and discharge (both p <0.001), and lower DASI scores (p = 0.003). A significant correlation was observed between plasma
Discussion
The DASI, established by Hlatky et al1 in 1989, seems to be a valuable tool that provides a standardized assessment of functional status and correlates well with peak oxygen uptake. This instrument is based on a patient's ability to perform common activities of daily living. Activities were chosen in a way to represent a wide range of cardiovascular stresses as well as several dimensions of personal health status (see Table 1). The DASI was developed in an attempt to overcome several
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2020, CollegianCitation Excerpt :Functional status, the ability to perform activities of daily living, has been associated with hospitalisation, mortality and predicted survival in patients with HF (Parissis et al., 2009). Studies have demonstrated that patients with poorer functional status had about twice the risk of experiencing a cardiac event, compared with patients with better functional status before and after controlling for potential confounders (Koch et al., 2007; Parissis et al., 2009); Wu et al. (2016). In addition, some studies have reported that functional status was closely related to HRQOL (Chu et al., 2014; Juenger et al., 2002) and poorer functional status significantly impaired HRQOL of patients with HF (Masoudi et al., 2004).