Clinical StudiesHuman SERCA2a levels correlate inversely with age in senescent human myocardium☆
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Abbreviations
SERCA2a
sarcoendoplasmic reticulum Ca2+-ATPase
I/R
ischemia-reperfusion
T
tau, the time constant of force decay
SI
simulated ischemia
[Ca2+]i
intramyocellular calcium
CAD
coronary artery disease
HTN
hypertension
IDDM
insulin-dependent diabetes mellitus
NIDDM
non–insulin-dependent diabetes mellitus
GERD
gastro-esophageal reflux disease
COPD
chronic obstructive pulmonary disease
CHF
congestive heart failure
LAD
left anterior descending coronary artery
RCA
right coronary artery
Cx
circumflex coronary artery
LVEF
left ventricular ejection fraction
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This work was supported in part by National Institutes of Health Grants HL-43696, HL-44186, and GM-08315.
Copyright © 1998 American College of Cardiology. Published by Elsevier Inc. All rights reserved.