Original contributionGiant cell tumor of tendon sheath is a polyclonal cellular proliferation
References (23)
- et al.
Giant cell tumor of tendon sheath and pigmented villonodular synovitis: Immunophenotype suggests a synovial cell origin
Hum Pathol
(1995) - et al.
Clonality in hepatocellular carcinoma: Analysis of methylation pattern of polymorphic X-chromosome-linked phosphoglycerate kinase gene in females
Hepatology
(1995) - et al.
Cytogenetic findings in a case of nodular fasciitis of the breast
Cancer Genet Cytogenet
(1995) - et al.
Gliosis specimens contain clonal cytogenetic abnormalities
Cancer Genet Cytogenet
(1993) - et al.
Methylation patterns at the hypervariable X-chromosome locus DXS255 (M27 beta): Correlation with X-inactivation status
Genomics
(1990) - et al.
Cytogenetic evidence of clonality in a case of pigmented villonodular synovitis
Cancer
(1991) - et al.
Chromosome aberrations in tenosynovial giant cell tumors and nontumorous synovial tissue
Genes Chromosomes Cancer
(1993) Hereditary cancer, oncogenes, and antioncogenes
Cancer Res
(1985)- et al.
Methylation of HpaII and HhaI sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation
Am J Hum Genet
(1992) - et al.
Pigmented villonodular synovitis, bursitis, and tenosynovitis
Arch Pathol
(1941)
Trisomy 5 and trisomy 7 are nonrandom aberrations in pigmented villonodular synovitis: Confirmation of trisomy 7 in uncultured cells
Genes Chromosomes Cancer
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RNAscope CSF1 chromogenic in situ hybridization: a potentially useful tool in the differential diagnosis of tenosynovial giant cell tumors
2021, Human PathologyCitation Excerpt :Tenosynovial giant cell tumors (TGCT), initially described by Jaffe in 1941 [1], are relatively common tumors that typically arise in association with the synovium of tendon sheaths, joints, or bursae [2]. Thought for decades to represent a non-neoplastic and most likely reactive process [3], cytogenetic studies in the 1990s demonstrated recurrent cytogenetic aberrations typically involving chromosome 1p, suggesting instead neoplastic etiology [4–7]. This hypothesis was elegantly confirmed in 2006 by West et al, who demonstrated fusions of the CSF1 (colony stimulating factor-1) gene at 1p13 with the COL6A3 (collagen type VI alpha 3) gene at 2q35 in roughly one-third of cases [8].
Tenosynovial giant cell tumor of the distal tibiofibular joint
2021, Radiology Case ReportsRadiation therapy for infiltrative giant cell tumor of the tendon sheath
2012, Journal of Hand SurgeryCitation Excerpt :She had 2 previous excisions at another center; she was referred for radiation therapy but refused treatment. Complete surgical excision of GCTTS remains the treatment of choice.26 Multiple recurrences and excisions increase morbidity and may rarely lead to amputation.3,8,27–29
Bilateral tenosynovial giant cell tumor of the knee accompanied by chronic ACL tear
2012, Journal of Orthopaedic ScienceTumors of Synovial Tissue
2010, Bone and Soft Tissue Pathology