The clinical spectrum of early lyme borreliosis in patients with culture-confirmed erythema migrans**,***
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Spirochaetes Diseases of the Tropics
2023, Manson's Tropical Diseases, Fourth EditionLyme Disease in Children
2022, Infectious Disease Clinics of North AmericaEarly Lyme Disease (Erythema Migrans) and Its Mimics (Southern Tick-Associated Rash Illness and Tick-Associated Rash Illness)
2022, Infectious Disease Clinics of North AmericaCitation Excerpt :The higher proportion of EM cases in recent years might be a consequence of fewer reported cases of extracutaneous manifestations of Lyme borreliosis due to more strict requirements for the diagnosis of extracutaneous manifestations and/or better and earlier recognition and treatment of early Lyme borreliosis. In the United States, only about 1 in 4 patients (14%–32%) with EM recall a previous tick bite at the site of the skin lesion.15–18 In European studies, the proportion of patients recalling a tick bite is substantially higher and exceeds 50%.13,16,18–20
79-Year-Old Woman With Confusion, Facial Numbness, and Rash
2022, Mayo Clinic ProceedingsCitation Excerpt :Other nonspecific Lyme-associated findings this patient presented with included fatigue (seen in 54% of Lyme neuroborreliosis cases), headache (42%), and regional lymphadenopathy (16%).4 Laboratory work-up may reveal nonspecific findings such as leukocytosis; elevated inflammatory markers; and mildly elevated liver function tests,4 consistent with this patient’s nonspecific laboratory work-up. No imaging findings are specific for Lyme neuroborreliosis, although nonspecific frontal cortex white matter changes may be seen.12
Early localized lyme disease
2022, Visual Journal of Emergency Medicine
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Presented in part at the VI International Conference on Lyme Borreliosis, Bologna, Italy, June 1994.
- ***
This work was supported in part by Cooperative Agreement No. U50/ CCU 206605 from the Centers for Disease Control and Prevention (CDC) and by Grant No. R01-AR41508 from the National Institute of Musculoskeletal and Skin Diseases (NIAMSD). The contents of this report are solely the responsibility of the authors and do not necessarily represent the official views of the CDC or the NIAMSD.