Sensitivities and Specificities for Detecting Serious Infection (n = 50) or No Serious Infection (n = 390) Among All Children with C-Reactive Protein (CRP) Measurement (n = 440)
| SI (n = 50) | No SI (n = 390) | Sensitivity (95% CI) | Specificity (95% CI) | Positive Predictive Value (95% CI) | Negative Predictive Value (95% CI) | LR+ | LR− | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Yes | No | Yes | No | |||||||
| CRP >20 mg/L | 26 | 24 | 182 | 208 | 52.0 (38.2–65.8) | 53.3 (48.4–58.3) | 12.5 (8.0–17.0) | 89.7 (85.7–93.6) | 1.1 (0.8–1.5) | 0.9 (0.7–1.2) |
| CRP >80 mg/L | 14 | 36 | 52 | 338 | 28.8 (15.6–40.4) | 86.7 (83.3–90.0) | 21.2 (11.3–31.1) | 90.4 (87.4–93.4) | 2.1 (1.3–3.5) | 0.8 (0.7–1.2) |
CI, confidence interval; LR+, positive likelihood ratio; LR−, negative likelihood ratio; SI, serious infection (defined as serious illness or referral).