Characteristics of Children with (n = 440) and without (n = 66) C-Reactive Protein Measurement (CRP)
| Children with CRP measured (n = 440) | Children without CRP measured (n = 66) | |
|---|---|---|
| Age (months)* | ||
| Mean (SD) | 25 (17) | 30 (18) |
| Median (range) | 20 (3–70) | 28 (3–66) |
| Male sex | 254 (57.7) | 35 (53.0) |
| Immigrant (yes) | 228 (51.8) | 31 (47.0) |
| Face-to-face contact with a general practitioner at presentation | 327 (74.3) | 44 (66.7) |
| Antibiotic prescriptions before presentation | 37 (8.4) | 7 (10.6) |
| Referral at initial presentation† | 18 (4.1) | 8 (12.1) |
| Serious illness at presentation‡ | 25 (5.7) | 8 (12.1) |
| SI at presentation§ | 30 (6.8) | 10 (15.2) |
| Referral after 1 week | 34 (7.7) | 8 (12.1) |
| Serious illness after 1 week | 39 (8.9) | 8 (12.1) |
| SI after 1 week | 50 (11.4) | 10 (15.2) |
| Antibiotic prescriptions after 1 week | 181/432 (41.9) | 23/58 (39.7) |
Data are n (%) unless otherwise indicated.
↵* Significant difference (mean difference, 5.7; 95% confidence interval, 1.2–10.1).
↵† Significant difference (χ2 = 7.593; df = 1; P = 0.006)
↵‡ Significant difference (χ2 = 3.904; df = 1; P = 0.048)
↵§ Significant difference (χ2 = 5.474; df = 1; P = 0.019).
SD, standard deviation; SI, serious infection (defined as a serious illness or referral).