| Type of Acne | Treatment | FDA Pregnancy Drug Class | Evidence Rating |
|---|---|---|---|
| Noninflammatory | |||
| Comedonal | Azelaic acid | B | Likely to be beneficial |
| Inflammatory | |||
| Mild to moderate | Azelaic acid + | B | Likely to be beneficial |
| Benzoyl peroxide or | C | Beneficial | |
| Topical erythromycin or | B | Beneficial | |
| Topical clindamycin + | B | Beneficial | |
| Benzoyl peroxide | C | Beneficial | |
| Moderate to severe | Oral erythromycin or | B | Likely to be beneficial |
| Oral cephalexin + | B | * | |
| Benzoyl peroxide with or without | C | Beneficial | |
| Azelaic acid or | B | Likely to be beneficial | |
| Intralesional steroid injections | C | * | |
| Fulminant | Oral erythromycin + | B | Likely to be beneficial |
| Benzoyl peroxide + | C | Beneficial | |
| Azelaic acid + | B | Likely to be beneficial | |
| Oral prednisone(short-term) | C | * |
Data from Ref. 37.
↵* Evidence of a drug's benefit is not discussed in Ref. 37.