Table 1. Comparison of the CHADS2 and CHA2 DS2-VASc* Risk Stratification Scores for Subjects With Nonvalvular Atrial Fibrillation5
DefinitionPossible ScoreStroke Risk Stratification
CHADS2 and CHA2DS2-VASc ScoresAdjusted Stroke Rate (% per year)
CHADS2 acronymCHADS2 acronym
    Congestive HF1    01.9
    Hypertension1    12.8
    Age ≥75 years1    24.0
    Diabetes mellitus1    35.9
    Stroke/TIA/TE2    48.5
    Maximum score6    512.5
CHA2DS2-VASc acronymCHA2DS2-VASc acronym
    Congestive HF1    00
    Hypertension1    11.3
    Age ≥75 years2    22.2
    Diabetes mellitus1    33.2
    Stroke/TIA/TE2    44.0
    Vascular disease (prior MI, PAD, or aortic plaque)1    56.7
    Age 65 to 74 years1    69.8
    Sex category (eg, female sex)1    79.6
    Maximum score9    86.7
  • These adjusted stroke rates are based on data for hospitalized patients and atrial fibrillation and were published in 2001.8 Because stroke rates are decreasing, actual stroke rates in contemporary nonhospitalized cohorts might vary from these estimates.

  • Adjusted stroke rate scores are based on data from Lip and colleagues.9 Actual rates of stroke in contemporary cohorts might vary from these estimates.

    AF = atrial fibrillation

  • * CHADS2 = congestive heart failure; hypertension; age ≥75 years; diabetes mellitus, prior stroke or transient ischemic attack (TIA), or thromboembolism (doubled). CHA2DS2-VASc = congestive heart failure; hypertension; age ≥75 years (doubled); diabetes mellitus; prior stroke or TIA or thromboembolism (doubled); vascular disease; age 65 to 74 years; sex category.

  • HF, heart failure; MI, myocardial infarction; PAD, peripheral artery disease; TE, thromboembolic.9,10