Table 2. Associated Etiologies of Upper Gastrointestinal Bleeding, By Age10,12,25
Age GroupEtiology
NeonateSwallowed maternal blood
Gastritis
Necrotizing enterocolitis
Coagulopathy in the presence of infection
Congenital coagulation deficiency
Esophagitis
Vascular malformation
Hemorrhagic disease of the newborn
Idiopathic
1 Month-1 yearPeptic ulceration
Curling ulcer
Duplication cyst
Foreign body
Gastric or esophageal varices
Vascular malformation
Bowel obstruction
Epistaxis
Hemoptysis
Reflux esophagitis
Stress gastritis
Medication-induced gastritis (eg, NSAIDs or aspirin use)
Caustic ingestion
1–5 YearsPeptic ulceration
Stress gastritis
Medication-induced gastritis (eg, NSAIDs or aspirin use)
Varices
Epistaxis
Hemoptysis
Mallory-Weiss tear
Gastroesophageal reflux
Caustic ingestion
Bowel obstruction
Vasculitis
Crohn disease
Hemophilia
5–18 YearsVarices
Peptic ulceration
Coagulation disorders
Immune thrombocytopenic purpura
Chemotherapy
Crohn disease
H. pylori gastritis
Gastroesophageal reflux
Mallory-Weiss tear
Caustic ingestion
  • NSAID, nonsteroidal anti-inflammatory drug.