| Histological Subtype | Targets | Drugs |
|---|---|---|
| Non squamous-cell carcinoma | Anti-EGFR (T790 mol/L) | AZD-9291 CO-1686 |
| Anti-ALK | Ceritinib | |
| Anti-MEK | Selumetinib | |
| Anti-BRAF | Dabrafenib | |
| Anti-HER2 | Trastuzumab | |
| Pertuzumab | ||
| Anti-MET | Onartuzumab | |
| Tivantinib | ||
| Cabozantinib | ||
| Crizotinib | ||
| Anti-RET | Cabozantinib | |
| Squamous-cell carcinoma | Anti-EGFR | Necitumumab |
| Anti-FGFR1 | Ponatinib | |
| Dovitinib | ||
| Cediranib | ||
| Anti-DDR2 | Dasatinib |