| Categories | Population Groups | Description |
|---|---|---|
| High risk of exposure or infection with Mycobacterium tuberculosis10,12,58 | Close contact | Children, adolescents, or adults with close contact with high-risk adults |
| Congregated living conditions | Employees or residents of long-term care facilities, correctional facilities, homeless shelters | |
| Foreign born | People who moved from countries with a high burden of TB to the United States (<5 years) | |
| High risk of LTBI progression to TB disease10,12,58 | History of TB | People acquiring latent TB infection within the previous 2 years or people with previous untreated/ineffective treatment of active TB with no sign of active TB at the time of starting latent TB treatment |
| Age | Children <4 years | |
| Substance use | People who inject illicit drugs | |
| Immunosuppression | People with poor nutrition status; previous surgical interventions (e.g., gastrointestinal surgical procedures); immunosuppressive medications (e.g., tumor necrosis factor-α antagonists, chronic corticosteroid use); immunocompromising conditions (e.g., HIV, chronic renal failure, diabetes mellitus, cancer) |
HIV, human immunodeficiency virus; TB, tuberculosis.