| Patients born between 1945 and 1965 or with risk factors should be screened for hepatitis C. | B |
| Patients for whom there is no contraindication should be offered treatment for hepatitis C. | A |
| Patients with the hepatitis C genotype 1 should be treated with triple therapy (peginterferon-α, ribavirin, and a protease inhibitor). | A |
| Patients without documented immunity to hepatitis A and B should be offered vaccination. | C |
| Patients with chronic hepatitis C should be encouraged to abstain from alcohol and offered treatment if needed. | C |
| Nonsteroidal anti-inflammatory drugs should be avoided in patients with cirrhosis. Acetaminophen and opioids can be used at low doses if needed. | C |
| Statin drugs may be used in patients with hepatitis C if serum aminotransferase levels are <5 times the upper limit of normal. | C |
| Patients with cirrhosis due to hepatitis C should be screened for hepatocellular carcinoma with annual ultrasound testing. | C |