| Estrogen | Asks about estrogen use in the past 2 years. Also asks about menopausal status and allows different estrogen effects depending on menopausal status | Does not specifically ask about estrogen use in the past 2 years |
| Vegetable intake | “In the past 30 days, about how many servings per week of vegetables or leafy green salads did you eat?” (cups) | Vegetables quantified according to grams per day based on detailed food frequency questionnaire |
| Family history of colorectal cancer | Number of first-degree relatives with a history of cancer of the colon or rectum | Family history of colon cancer in first-degree relative (yes or no) |
| Activity | Defined according to the number of hours of activity in the past week, but also requires detailed information about how many months the participant was active in the past year | Only asked about current activity level |
| Nonsteroidal anti-inflammatory drugs and aspirin | Regular use defined as 3 times per week | Regular use was defined as twice per week |