| Characteristics | Developed Colorectal Cancer | Patients with Missing Data | |
|---|---|---|---|
| No (n = 99,292) | Yes (n = 1,276) | ||
| Mean age, years (SD)* | 59.5 (8.8) | 64 (7.9) | 0 (0.0) |
| Race/ethnicity* | 0 (0.0) | ||
| Black | 19,694 (19.8) | 347 (27.2) | |
| Hawaiian | 7,464 (7.5) | 77 (6) | |
| Japanese | 26,500 (26.7) | 413 (32.4) | |
| Latino | 21,730 (21.9) | 194 (15.2) | |
| White | 23,904 (24.1) | 245 (19.2) | |
| Mean pack-years smoking (SD)* | 6.6 (12.1) | 7.4 (12.8) | 3,739 (3.7) |
| Alcohol intake (mean drinks/day [SD])*† | 0.3 (1.1) | 0.4 (1.6) | 0 (0.0) |
| Mean years of education (SD) | 13.0 (3.3) | 12.8 (2.9) | 1,255 (1.2) |
| Family history of colon cancer* | 9,165 (9.2) | 174 (13.6) | 12,707 (12.6) |
| Mean body mass index (SD) | 26.4 (5.5) | 26.6 (5.7) | 2,346 (2.3) |
| Regular use of aspirin‡ | 4,971 (4.9) | ||
| No | 61,593 (62) | 806 (63.2) | |
| Yes, not currently | 19,193 (19.3) | 234 (18.3) | |
| Yes, currently | 18,506 (18.6) | 236 (18.5) | |
| Regular use of multivitamins*§ | 53,596 (54) | 625 (49) | 2,649 (2.6) |
| Diabetes* | 10,910 (11) | 188 (14.7) | 0 (0.0) |
| Mean hours of moderate activity/day (SD) | 1.1 (1.2) | 1 (1.2) | 2,420 (2.4) |
| History of cancer | 11,576 (11.7) | 151 (11.8) | 0 (0.0) |
| Preference for well-done meat* | 53,082 (53.5) | 739 (57.9) | 1,287 (1.3) |
| Mean intake of red meat per day, oz (SD)* | 1.7 (1.6) | 1.6 (1.4) | 0 (0.0) |
| Regular use of NSAIDs*‡ | 6,488 (6.2) | ||
| No | 62,132 (62.6) | 849 (66.5) | |
| Yes, not currently | 21,284 (21.4) | 266 (20.8) | |
| Yes, currently | 15,876 (16) | 161 (12.6) | |
| Estrogen use*‖ | 3,277 (3.1) | ||
| No | 53,754 (54.1) | 709 (55.6) | |
| Yes, not currently | 17,752 (17.9) | 278 (21.8) | |
| Yes, currently | 27,786 (28) | 289 (22.6) | |
Data are n (%) unless otherwise indicated. The Multiethnic Cohort study enrolled an ethnically diverse mix of residents from Hawaii and California between 1993 and 1996.
↵* Statistically significant in univariate analysis (P < .05).
↵† One alcoholic drink is defined as 1 oz of alcohol, which is approximately equivalent to one 12 oz beer, one 4 oz glass of wine, or one shot of liquor.
↵‡ At least twice a week for 1 month or longer.
↵§ At least once per week for the past year.
↵‖ Estrogen use was defined as female hormones administered by pill, injection, or patch for menopause or other reasons.
NSAID, nonsteroidal anti-inflammatory drug; SD, standard deviation.