Table 1. Classification of Eosinophilic Gastrointestinal Diseases
TypeSymptomsTreatment
MucosalAnemia from iron deficiency or occult fecal blood loss, protein-losing enteropathy, and malabsorption, peripheral edema Most frequent type
Elimination diet
Cromoglycate
Ketotifen
Glucocorticosteroids
Azathioprine
SubmucosalBowel wall thickening results in obstructive signs (colicky pain, nausea, vomiting) At risk for bowel obstructionMontelukast
Imatinib mesylate
Omalizumab
SerosalAssociated with ascites, bloating, high peripheral eosinophilia, peritonitis Rarest formHistamine 2 receptor blockers
Proton pump inhibitors
  • Adapted from Refs. 69.