Positive Predictive Value, Sensitivity, and Specificity of Prostate-Specific Antigen (PSA) as Screening Parameter.
| Reference | Population with PSA > 4 ng/mL(%) | Positive Predictive Value(%) | Sensitivity(%) | Specificity(%) |
|---|---|---|---|---|
| Bangma et al14 | 10.31 | 30.90 | ||
| Brett15 | 9.50 | 66.67 | 18.00 | |
| Bretton16 | 13.00 | 27.91 | 92.31 | |
| Gustafsson et al17 | 17.17 | 17.00 | 80.00 | |
| Higashihara et al7 | 11.27 | 24.00 | 92.30 | 63.10 |
| Horninger et al18 | 8.88 | 25.32 | ||
| Horninger et al18 | 12.50 | 22.18 | ||
| Imai et al19 | 4.46 | 27.50 | 73.33 | 99.75 |
| Imai et al20 | 5.13 | 45.10 | 80.40 | |
| Jubelirer et al3 | 12.60 | 30.00 | 100.00 | 100.00 |
| Maattanen et al5 | 8.47 | 27.00 | ||
| Reissigl et al21 | 10.74 | 18.00 | ||
| Stenman et al22 | 57.00 | 97.00 | ||
| Tsukamoto et al23 | 4.30 | 23.20 | 88.90 | |
| Pooled results | 10.10 | 25.10 | 72.10 | 93.20 |
Positive predictive value of PSA = percent of positive biopsies/total positive PSA.