Groups Randomized to Paroxetine or Placebo with at Least Four Treatment Sessions.
| >4 sessions*n = 333 | Paroxetinen = 152 | Placebon = 181 | ||||
|---|---|---|---|---|---|---|
| No. | Percent | No. | Percent | No. | Percent | |
| Demographics | ||||||
| Sex (female) | 172 | 52 | 73 | 48 | 99 | 55 |
| Age cohort >59 y | 211 | 63 | 95 | 62 | 116 | 64 |
| Ethnicity (majority) | 271 | 81 | 126 | 83 | 143 | 80 |
| Married | 178 | 54 | 78 | 51 | 100 | 55 |
| Employed | 124 | 37 | 58 | 38 | 66 | 36 |
| Income, y <$20,000 | 162 | 49 | 79 | 52 | 83 | 46 |
| Veteran | 88 | 26 | 41 | 27 | 47 | 26 |
| Minor depression | 159 | 48 | 71 | 47 | 88 | 49 |
| Education <13 y | 156 | 47 | 72 | 47 | 84 | 46 |
| Mean | SD | Mean | SD | Mean | SD | |
| Patient beliefs (PAB) | ||||||
| Biological beliefs | 3.2 | 1.1 | 3.2 | 1.0 | 3.2 | 1.2 |
| Psychological beliefs | 3.7 | 1.0 | 3.7 | 1.0 | 3.7 | 1.0 |
| SCL scales | ||||||
| Depression | 1.5 | 0.6 | 1.5 | 0.6 | 1.4 | 0.7 |
| Somatization | 1.0 | 0.7 | 1.1 | 0.7 | 1.0 | 0.7 |
| Anxiety | 0.9 | 0.6 | 0.9 | 0.6 | 0.9 | 0.7 |
| Hostility | 0.7 | 0.7 | 0.8 | 0.6 | 0.7 | 0.7 |
| Interpersonal sensitivity | 1.0 | 0.7 | 1.0 | 0.7 | 1.0 | 0.7 |
| SF-36 scales | ||||||
| General health | 53.3 | 22.5 | 52.2 | 23.0 | 54.2 | 22.1 |
| Physical function | 60.3 | 28.8 | 58.9 | 28.4 | 61.4 | 29.3 |
| Role physical | 38.3 | 40.1 | 38.3 | 40.9 | 38.2 | 39.6 |
| Role emotional | 34.9 | 38.0 | 33.8 | 37.4 | 35.9 | 38.5 |
| Pain | 52.2 | 24.4 | 52.4 | 24.4 | 52.0 | 24.4 |
| Vitality | 32.8 | 19.4 | 32.2 | 19.4 | 33.2 | 19.5 |
| Mental health | 53.8 | 17.2 | 52.8 | 17.0 | 54.7 | 17.3 |
| Social function | 58.8 | 25.0 | 58.0 | 26.1 | 59.4 | 24.1 |
* There were no significant differences on any variable between groups randomized to paroxetine and placebo.
PAB = Patient Attitudes and Beliefs Scale, SCL = Hopkins Symptom Checklist-57 scales, SF-36 = Medical Outcomes Study Short-Form 36 Scale.