Table 1.

Relative Risks of Clinical Events with Estrogen-Progestin Therapy Compared with Placebo in The Women's Health Initiative Randomized Trial^2,4–10

Event (Reference)	Overall Hazard Ratio	Nominal 95% CI	Adjusted 95% CI
Coronary heart disease (4)	1.23	0.99 to 1.53	NR
Stroke (4, 5)	1.31	1.03 to 1.68	0.93 to 1.84
Venous thromboembolism (6)	2.06	1.57 to 2.70	NR
Breast cancer, invasive (7, 8)	1.24	1.01 to 1.54	0.94 to 1.33
Colorectal cancer (9)	0.56	0.38 to 0.81	0.33 to 0.94
Hip fracture (10)	0.67	0.47 to 0.96	0.41 to 1.10
Any fracture (10)	0.76	0.69 to 0.83	NR