Key Pharmacodynamic Properties for Different Insulin Preparations6,28
| Insulin Preparation | Onset of Action | Peak Action (hours) | Duration of Action (hours) |
|---|---|---|---|
| Lispro | 5 to 15 minutes | 1 to 2 | 3 to 4 |
| Aspart | 5 to 15 minutes | 1 to 2 | 3 to 4 |
| Regular | 30 to 60 minutes | 2 to 4 | 6 to 8 |
| NPH | 1 to 3 hours | 5 to 7 | 13 to 16 |
| Lente | 1 to 3 hours | 4 to 8 | 13 to 20 |
| Ultralente | 2 to 4 hours | 8 to 14 | <20 |
| Glargine | 2 to 4 hours | Flat | >24 |
NPH, neutral protamine Hagedorn.