Identification and Management for Patients at Increased Risk of Ovarian Cancer Based on Family Cancer History
| Identification of persons at ‘increased risk’ because of family cancer history |
| Ovarian cancer risk increased among: |
| Women who have a mother and/or sister(s), daughter(s), or grandparent(s) with breast cancers and/or ovarian cancers, especially if one or more is diagnosed before age 50 years. |
| Women with a personal or family history of breast, endometrial, or colorectal cancer. |
| Surveillance recommendations for persons at ‘increased risk’ because of family cancer history |
| All ages: |
| Evaluate comprehensive family history of cancer and overall health status of patient. |
| Discuss risk status, and overall health status with patient, and plans for ongoing surveillance including possible referral to specialist, ultrasound monitoring, pelvic examination and CA-125 testing. |
| Consider whether involvement in a prevention trial is an option. |
| Consider a consultation with a genetic counselor for risk assessment and possible genetic testing. |