Effects of Obesity on Knee Osteoarthritis
| Authors | Assessment of Obesity | Results | Effect* (OR [RR]) |
|---|---|---|---|
| Abbate et al (30) | BMI: heaviest quartile vs lowest quartile | Increased diagnosis of knee OA | 5.27 (3.05–9.13) |
| Weight: heaviest quartile vs lowest quartile | Increased diagnosis of knee OA | 5.28 (3.05–9.16) | |
| Grotle et al (31) | BMI >30 | Increased diagnosis of new knee OA within 10 years | 2.81 (1.32–5.96) |
| Holmberg et al (32) | BMI increase from 23 to 25 | Increased radiograph diagnosis of knee OA | 1.6 (0.9–3.1) |
| Liu et al (33) | BMI >30 vs BMI <22.5 | Increased rates of knee replacement | 10.51 (7.85–14.08) |
| Patterson et al (12) | BMI >35 | Increased rates of knee replacement | 11.7 |
* All odds ratio (OR) and relative risk (RR) are compared to women with body mass index (BMI) <25, unless otherwise noted.
OA, osteoarthritis.