Yamaguchi Criteria*
| Major Criteria | Minor Criteria | Exclusion Criteria |
|---|---|---|
| • Arthralgia, >2 weeks | • Sore throat | • Infection, especially sepsis |
| • Fever, >39°C, intermittent ≥1 week | • Lymphadenopathy and/or splenomegaly | • Epstein-Barr infection |
| • Typical rash (macula popular, nonpruritic) | • Abnormal liver function test | • Malignancy |
| • WBC >10,000 (>80% granulocytes) | • Rhematoid factor and ANA negative | • Inflammatory disease |
* The Yamaguchi criteria require the presence of 5 criteria to diagnose Still disease, and at least 2 must be major criteria.12
WBC, white blood cell; ANA, antinuclear antibody.