Hypercoagulable Etiologies
| Thrombophilic Disorders | Local Factors | ||
|---|---|---|---|
| Inherited Disorders | Acquired Disorders | Inflammatory | Related to Surgery |
| Factor V Leiden mutation | Myeloproliferative disorders | Cirrhosis | Post liver transplant |
| Prothrombin mutation | Malignancy | Sepsis | Splenectomy |
| Antithrombin III | Antiphospholipid syndrome | Pancreatitis/cholecystitis | Colectomy |
| Protein C deficiency | Anticardiolipin antibody | Diverticulitis | Umbilical vein catheterization |
| Protein S deficiency | Paroxysmal nocturnal hemoglobinuria | Appendicitis | Portacaval shunting |
| Hyperhomocysteinemia | Peptic ulcer disease | ||
| Oral contraception pills | Inflammatory bowel disease | ||
| Pregnancy/postpartum | Blunt abdominal trauma | ||