Prophylactic Antibiotics in Patients on Peritoneal Dialysis
| Condition | Drug | Adult Dose |
|---|---|---|
| Prophylactic regimen for dental, oral, or upper respiratory procedures | ||
| Standard regimen | Amoxicillin | 2 g orally (po, per os) 1 hour before procedure |
| Penicillin allergy | Clindamycin, Cephalexin, Cefadroxil, Azithromycin, or Clarithromycin | 600 mg po 1 hour before procedure; 2 g po 1 hour before procedure; 500 mg po 1 hour before procedure |
| Patients unable to take oral medication | Ampicillin | 2 g IV/IM 30 minutes before procedure |
| Penicillin allergy and cannot take oral medications | Clindamycin or Cefazolin | 600 mg IV 30 minutes before procedure; 1 g IV/IM 30 minutes before procedure |
| Prophylactic regimen for genitourinary/gastrointestinal (excluding esophageal) procedures | ||
| Standard regimen | Ampicillin and Gentamycin plus Amoxicillin or Ampicillin | 2 g IM/IV 30 minutes before procedure; 1.5 mg/kg (maximum 120 mg) IM/IV 30 minutes before procedure; 1 g po 6 hours after the initial dose; 1 g IM/IV 6 hours after the initial dose |
| Patients allergic to penicillins | Vancomycin Plus gentamycin | 1 g IV over 1 to 2 hours completing within 30 minutes of the starting procedure; 1.5 mg/kg (maximum 120 mg) IM/IV 30 minutes before procedure |
IV, intravenously; IM, intramuscularly.