Table 2.

Less Common Causes of Leg Edema in the United States

UnilateralBilateral
Acute (<72 hours)ChronicAcute (<72 hours)Chronic
Ruptured Baker’s cystSecondary lymphedema (tumor, radiation, surgery, bacterial infection)Bilateral deep vein thrombosisRenal disease (nephrotic syndrome, glomerulonephritis)
Ruptured medial head of gastrocnemiusPelvic tumor or lymphoma causing external pressure on veinsAcute worsening of systemic cause (heart failure, renal disease)Liver disease
Compartment syndromeReflex sympathetic dystrophySecondary lymphedema (secondary to tumor, radiation, bacterial infection, filariasis)
Pelvic tumor or lymphoma causing external pressure
Dependent edema
Diuretic-induced edema
Dependent edema
Preeclampsia
Lipidema8
Anemia