Table 3.

Implications and Example of Application of RE-AIM Framework

Goal: To identify interventions that can:Example Smoking Study*Example Diabetes Study
Reach large numbers of people, especially those who can most benefit.76% participation among low income, young female smokers. Participants appeared representative.50% participation among primary care diabetes patients. Participants representative on key variables.
Be effective in producing targeted outcomes at reasonable cost and produce minimal negative impacts, relative to alternatives.11% vs. 7% cessation at 6 weeks, P < .05 Quality of life and/or adverse consequences were not measured. Intervention time reported but costs not calculated.Significant improvement on both preventive assessments and behavioral counseling aspects of care. Both conditions improved on quality of life. Intervention costs estimated at $222 per patient.
Be widely adopted by many types of settings.4 of 4 clinics with most diverse populations in the metro area.6% of family medicine and internal medicine physicians throughout Colorado. Those participating were representative on variety of practice characteristics.
Be consistently implemented by staff members with moderate levels of training and expertise.85%–100% implementation by usual clinical staff for all treatment components except calls (43%).97% completion of key intervention components.
Produce replicable and long-lasting maintenance effects.Cessation differences (11.6% vs. 8.5%) no longer significant.Effectiveness measures were of equal magnitude and significance at 12-month follow-up as initial 6-month assessment.
  • * Information from Glasgow et al.45

  • Information from Glasgow et al.46