Table 2.

Nonstudy Analgesic Use Reported by Sample

None*MinimalHigh
Guaifenesin N (%)Placebo N (%)Guaifenesin N (%)Placebo N (%)Guaifenesin N (%)Placebo N (%)
Trial 1
 Day 16 (46%)4 (33%)4 (31%)4 (33%)3 (23%)4 (33%)
 Day 210 (77%)5 (42%)2 (15%)3 (25%)1 (8%)4 (33%)
Trial 2
 Day 16 (55%)1 (10%)2 (18%)3 (10%)3 (27%)6 (60%)
 Day 28 (73%)3 (30%)2 (18%)3 (30%)1 (9%)4 (40%)
Trial 3
 Day 16 (75%)1 (11%)2 (25%)5 (56%)0 (0%)3 (33%)
 Day 26 (75%)0 (0%)2 (25%)5 (56%)0 (0%)4 (44%)
  • * No reported nonstudy analgesic medication used.

  • Nonstudy analgesic use reported to be no more than 800 mg/day of ibuprofen, 300 mg/day of naproxen, 1250 mg/day of acetaminophen, or an equivalent combination of analgesics.

  • Nonstudy analgesic use reported to be any combination of more than 800 mg/day of ibuprofen, 300 mg/day of naproxen, or 1250 mg/day of acetaminophen.