Table 4.

Adjusted* Odds Ratios (OR) with 95% Confidence Intervals (CI) for Breast Cancer among Symptomatic Women Compared with Asymptomatic Women Stratified by Diagnostic and Screening Exams, Prior Screening History, and Symptom History

SymptomDiagnostic ExamsScreening Exams
No Prior ExamPrior Exam with No SymptomsPrior Exam with SymptomsNo Prior ExamPrior Exam with No SymptomsPrior Exam with Symptoms
Any2.7 (2.0, 37.1)2.9 (1.9, 4.3)0.9 (0.4, 1.6)1.0 (0.1, 7.4)4.5 (2.3, 8.9)2.1 (0.5, 8.3)
Lump12.2 (2.8, 53.5)4.1 (2.7, 6.2)1.2 (0.6, 2.5)3.5 (0.5, 27.0)17.2 (8.0, 37.1)3.9 (0.8, 20.0)
Nipple discharge13.3 (2.6, 66.9)1.0 (0.3, 3.4)0.5 (0.1, 2.5)3.0 (0.4, 22.1)3.8 (0.5, 33.0)
Pain8.9 (1.6, 50.0)1.5 (0.6, 4.0)
Other6.4 (1.4, 29.7)1.5 (0.8, 2.9)0.6 (0.2, 1.6)0.8 (0.1, 6.0)
  • * Adjusted for age, body mass index, family history of breast cancer, previous breast biopsy, and hormone therapy use.

  • Symptoms reported at previous exam could have been any symptom.

  • Symptom categories are not mutually exclusive.