Table 2.

Breast Cancer Rates* and Adjusted Odds Ratios (OR) with 95% Confidence Intervals (CI) for Breast Cancer Associated with Breast Symptoms

SymptomDiagnostic ExamsScreening Exams
NBreast CancerOR (95% CI)NBreast CancerOR (95% CI)
NRateNRate
None9,249383411.0105,14665661.0
Any4,275283662.0 (1.6, 2.3)5,17767132.1 (1.6, 2.7)
Lump2,745229832.8 (2.3, 3.4)1,74038223.6 (2.6, 5.0)
Nipple discharge47025531.5 (1.0, 2.3)87310111.8 (1.0, 3.4)
Pain28715521.4 (0.8, 2.4)694691.5 (0.7, 3.4)
Other1,40058411.2 (0.9, 1.6)2,6722071.2 (0.8, 1.9)
  • * Rate of breast cancer diagnoses per 1000 women per year.

  • Adjusted for age, body mass index, family history of breast cancer, previous breast biopsy, and hormone therapy use.

  • Symptom categories are not mutually exclusive.