Appendix 1 Table 3.

Associations Between Symptom Severity and Perceived Relatedness to Medication Adherence to Blood Pressure Treatment Adherence (Changing or Stopping Medications Due to Side Effects) and (n = 1,423)

Symptom SeverityPerceived Related to Medication
Total with SymptomSomewhat or ModerateBig or Very BigpUnrelated to MedsRelated to Medsp
Any symptom1,423811612<0.001769654
 No adherence issue1,090 (76.6%)664 (81.9%)426 (69.6%)661 (86.0%)429 (65.6%)<0.001
 Yes adherence issue333 (23.4%)147 (18.1%)186 (30.4%)108 (14.0%)225 (34.4%)
Tiredness1,1028122900.006905197<0.001
 No adherence issue826 (75.0%)626 (77.1%)200 (69.0%)706 (78.0%)120 (60.9%)
 Yes adherence issue276 (25.0%)186 (22.9%)90 (31.0%)199 (22.0%)77 (39.1%)
Dizziness675560115<0.001442233<0.001
 No adherence issue467 (69.2%)406 (72.5%)61 (53.0%)336 (76.0%)131 (56.2%)
 Yes adherence issue208 (30.8%)154 (27.5%)54 (47.0%)106 (24.0%)102 (43.8%)
Leg swelling5834311520.344251,589<0.001
 No adherence issue435 (74.6%)326 (75.6%)109 (71.7%)339 (89.8%)96 (60.8%)
 Yes adherence issue148 (25.4%)105 (24.4%)43 (28.3%)86 (20.2%)62 (39.2%)
Cough5414281130.06424117<0.001
 No adherence issue392 (72.5%)318 (74.3%)74 (65.5%)323 (76.2%)69 (59.0%)
 Yes adherence issue149 (27.5%)110 (25.7%)39 (34.5%)101 (23.8%)48 (41.0%)
Urinary frequency8866961900.195922940.08
 No adherence issue662 (74.7%)527 (75.7%)135 (71.0%)453 (76.5%)209 (71.1%)
 Yes adherence issue224 (25.3%)169 (24.3%)55 (29.0%)139 (23.5%)85 (28.9%)
Sexual symptoms3842421420.07278106<0.001
 No adherence issue278 (72.4%)183 (75.6%)95 (66.9%)214 (77.0%)64 (60.4%)
 Yes adherence issue106 (27.6%)59 (24.4%)47 (33.1%)64 (23.0%)42 (39.6%)