Mean Scores, Number of un-Ratable Domains, Number of Domains Requiring Consensus and Arbitration*
| PRECIS-2 Domain | Mean Score* (± SD) | Number of Studies with Domains Not Ratable | Number of Studies Where Scoring Required a Consensus between an Explanatory (<3) or Pragmatic (>3) or If un-Ratable† | Number of Studies Where Scoring Required Arbitration by a Third Reviewer (EAH) |
|---|---|---|---|---|
| Eligibility criteria | 2.91 (±0.83) | 0/12 (0%) | 2/12 (17%) | 1/12 (8%) |
| Recruitment path | 2.54 (±0.69) | 0/12 (0%) | 1/12 (8%) | 0/12 (0%) |
| Setting | 2.50 (±0.97) | 1/12 (8%) | 2/12 (17%) | 0/11 (0%) |
| Organization | 2.86 (±0.69) | 4/12 (33%) | 4/12 (33%) | 0/12 (0%) |
| Flexibility (staff) | 2.62 (±0.92) | 3/12 (25%) | 4/12 (33%) | 2/12 (17%) |
| Flexibility (adherence) | 3.18 (±0.40) | 0/12 (0%) | 4/12 (33%) | 0/12 (0%) |
| Follow-up | 2.73 (±0.65) | 1/12 (8%) | 3/12 (25%) | 1/12 (8%) |
| Primary outcome | 3.27 (±0.79) | 0/12 (0%) | 4/12 (33%) | 0/12 (0%) |
| Analysis | 3.54 (±0.93) | 0/12 (0%) | 1/12 (8%) | 1/12 (8%) |
Abbreviation: PRECIS, PRagmatic Explanatory Continuum Indicator Summary.
*Mean ratings were calculated by averaging the domain score for each randomized controlled trial. If a domain was un-ratable the score was averaged over the number of studies with available rating data.
*PRECIS-2 ratings are presented as mean (±standard deviation).
†Consensus was reached between two primary raters (SZ and MM).