Table 1.

Effective Pharmacologic Methods for Reducing Pain with IUD Insertion

RecommendationStrength of RecommendationProsCons
Lidocaine-prilocaine cream and EMLA creamA8,12,1617,19Decreased pain with tenaculum placement, during uterine sounding, and with IUD insertionNot commonly stocked in clinics
Needs to be applied ∼5 to 15 minutes before procedure
10% lidocaine sprayA8,12,16,18Decreased pain with tenaculum placement, during sounding, and with IUD insertionNot commonly stocked in clinics
Needs to be applied ∼5 to 15 minutes before procedure
Lidocaine paracervical block
10-20 mL 1% lidocaine and 10 mL 2% lidocaine
A 8,12,2021Decreased pain with tenaculum placement, uterine sounding, IUD insertion
Decreased pain 5 minutes after placement
Pain with lidocaine injection
Tramadol 50 mg (orally)A12,13Decreased pain with IUD insertion, more pain reduction than naproxenNeeds to be taken 30 – 60 minutes before procedure
Naproxen 550 mg (orally)A12,13Decreased pain with IUD insertion, decreased pain 5 minutes and 15 minutes after insertionNeeds to be taken 30 – 60 minutes before procedure
  • Abbreviations: EMLA, Eutectic Mixture of Local Anesthetics; IUD, Intrauterine Device.