Table 3.

Excited or Apprehensive—Likely Uses of Artificial Intelligence/Machine Learning from a Complexity Perspective

Primary Care FunctionExcited/Less Complex CareApprehensive/More Complex Care
AI/ML more likely to helpFactors making AI/ML less likely to help
Diagnose
  • Improve physician confidence to diagnose a patient concern likely explained by one diagnosis.

  • Possibly improve diagnosis of rare diseases.

  • More quickly sifting through and sizing up evidence.

    • Possibly better than doing your own Google or literature search.

    • More quickly and more focused searches with less time taken from actual patient care.

  • Complex interaction of multiple symptoms and possible diseases including psychosocial and social determinant effects that is too much for the computer to manage.

  • Actual diagnostic computer “nuts and bolts” can be nonsensical.

  • Diagnoses more accurate in AI/ML demonstrations with well-structured vignettes.

  • AI/ML diagnoses not likely to include contextual and relational factors.

Treat specific diseases
  • Better at judging the chances of what treatment will work best for what patient.

  • Helping the physician become a better “odds-maker.”

  • Greater objectivity—more evidentiary basis and less sense of exposure

  • Readiness to take on complex work that might otherwise have seemed “beyond my bandwidth” when not assisted by AI tools, especially for rarer diseases.

  • Noisy and inaccurate data in EHRs.

  • May only add real value for rarer diseases.

  • AI not successful at improving cancer treatment.

  • Using historical treatment data may not reflect newer approaches.

  • Many treatment decisions are based on a negotiation with the patient using patient-shared decision making.

  • Relationships of data elements in existing databases (EHRs, billing data, and so on) often non-linear with Pareto distributions, which makes mathematical predictions challenging.

Predict future health events
  • Identify patients at increased risk for hospitalization.

  • Predictions may not be actionable.

  • Existing models may give similar population estimates, but vary widely for individuals.

  • AI/ML predictions may not improve upon existing tools.

Decrease administrative burden
  • Getting through all those letters and forms with less burden.

  • For U.S. physicians mostly, decrease documentation time and burden.

  • Patient symptoms in primary care are often vague, and even human scribes do not agree how to document them.

  • Distinction between typing spoken words onto a clinic note versus increasing understanding.

  • Abbreviations: AI, artificial intelligence; ML, machine learning; EHR, electronic health record.