Sensitivity Analysis of Past-Year Experience of Cannabis Use Disorder (CUD) Symptoms and Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) CUD Category Among Survey Participants Who Used Cannabis for Pain and Who Used Cannabis for Other Reasons in the Past 30 Days, Excluding Participants Who Apply Cannabis Only (n = 21)
| Used cannabis for pain (n = 354) | Used cannabis for other reasons* (n = 558) | ||
|---|---|---|---|
| n (%) | n (%) | P value | |
| Individual CUD Symptoms | |||
| Tolerance | 57 (16.5) | 149 (26.8) | <0.001 |
| Withdrawal | 45 (12.8) | 118 (21.3) | 0.001 |
| Failed attempts to cut down | 12 (3.4) | 62 (11.2) | <0.001 |
| Craving | 84 (23.9) | 181 (32.8) | 0.004 |
| Uncontrolled escalation of use | 97 (27.5) | 219 (39.3) | <0.001 |
| Time spent | 6 (1.7) | 26 (4.7) | 0.018 |
| Continued use despite consequences | 13 (3.7) | 57 (10.3) | <0.001 |
| Interference with role obligations | 5 (1.4) | 48 (8.6) | <0.001 |
| Interpersonal problems | 9 (2.6) | 27 (4.8) | 0.086 |
| Hazardous situations | 46 (13.1) | 112 (20.1) | <0.001 |
| Gave up activities | 6 (1.7) | 45 (8.1) | <0.001 |
| Any CUD symptom | 194 (54.8) | 341 (61.1) | 0.059 |
| DSM-5 CUD Category | |||
| No CUD (0 to 1 symptom) | 257 (72.6) | 317 (56.8) | <0.001† |
| Mild CUD (2 to 3 symptoms) | 75 (21.2) | 124 (22.2) | |
| Moderate CUD (4 to 5 symptoms) | 19 (5.4) | 63 (11.3) | |
| Severe CUD (6+ symptoms) | 3 (0.8) | 54 (9.7) |