Quality-of-Life Score Spline Regression Analysis Slope Coefficients
| Coefficient | Std. Err. | P-Value | 95% Interval | |
|---|---|---|---|---|
| First segment slope spline (days 1 to 3) | ||||
| Referent Group (Placebo) | −3.31 | 0.76 | <0.001 | (−4.79, −1.82) |
| Vitamin C | 1.28 | 1.05 | 0.22 | (−0.78, 3.33) |
| Melatonin | 2.23 | 1.07 | 0.04 | (0.13, 4.34) |
| Second segment slope spline (days 3 to 9) | ||||
| Referent Group (Placebo) | −0.71 | 0.21 | 0.001 | (−1.11, −0.3) |
| Vitamin C | −0.45 | 0.29 | 0.12 | (−1.03, 0.12) |
| Melatonin | −1.16 | 0.30 | <0.001 | (−1.75, −0.57) |
| Third segment slope spline (days 9 to 13) | ||||
| Referent Group (Placebo) | −0.23 | 0.27 | 0.39 | (−0.76, 0.3) |
| Vitamin C | −0.02 | 0.38 | 0.96 | (−0.76, 0.72) |
| Melatonin | −0.23 | 0.39 | 0.56 | (−1, 0.54) |
Note: these slope coefficients represent change over a very short period of time, ie 3-4 days.
Correlates with Figure 3.